The Brigade has participated with personnel and materials in the 8th ISAF Mission for the constitution of the Mission Command in 2006.
Later it also provided personnel to the ISAF Command in 2009, in 2013 and in 2014.
The Support Brigade has contributed significantly over the years to the operational readiness of the NRDC-ITA (HQ) in the field of validation and shift work such as JTF HQ (Joint Task Force Headquarters, from 2015 to 2017) and NRF LCC (Born Response Force Land Component Command, since 2018).
In addition, the Grande Unità continuously provides shares of its staff to support all the contingents employed in the operating theatres in which Italy is present.
In the end, the Support Brigade actively contributed to the important national effort on the occasion of the epidemiological emergency by COVID-19, planning and coordinating the deployment of personnel and resources for the health and civil protection of the Lombardy Region as well as in the framework of the various operations conducted under the aegis of the Defense (Eos, Mercurio, Igea, Minerva, Fenice).