The first idea of creating a Museum for the Specialty of Grenadiers dates back to 5th March 1903 when a delegation of Officers from the two Regiments met in the Room of Historical Memories of the Barracks "Ferdinando of Savoy" in Rome; the delegation proposed to collect relics, historical documents and data in that location in order to "preserve the glories and the traditions of the Grenadiers Brigade". The initiative got many acceptances and the small Museum started an intense activity of recovery and promotions of the traditions of the "White Austrian Knot".
However, in the era of the War in Libya (1911), the quantity and the quality of the collected historical items imposed the need to be placed in a new more adequate location. That need was officially ratified in the Museum proceedings, in a report on 3rd July 1912: it indicated as possible location the Barracks "Umberto I" in Holy Cross in Jerusalem Square, in Rome. But the project was postponed because of the outbreak of the First World War.
At the end of the conflict, the Municipality of
Rome assigned an area in Holy Cross in Jerusalem Square as the new location; on
3rd July 1922, at the presence of Vittorio Emanuele III, the
foundation stone of the building was laid.
The Museum was built by Grenadiers volunteers with the monetary contribution of the Grenadiers of the whole Italy; at the presence of the Rulers of Savoy, it was inaugurated on 3rd June 1924, in the 265th year from the foundation of the Corps.
In July 1943 he survived in the bombing to the train station of San Lorenzo; in 1986 the patrimony of the Grenadiers Museum was devolved to the Ministry of Defence, by decree of the President, and became Unit of the Mechanized Brigade of "Sardinian Grenadiers".